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Nee Soon Clinic
15 Sept 2025
Enter Profhilo Neck, a bio-remodelling injectable that delivers hydration and skin quality improvement without adding volume.
Aging doesn’t stop at the face. The neck is often one of the first places to reveal fine lines, laxity, and crepey texture due to its thinner skin and frequent exposure to movement and sun. Traditional fillers may be too heavy or localized for this delicate area. Enter Profhilo Neck, a bio-remodelling injectable that delivers hydration and skin quality improvement without adding volume.
In this article, we explore what makes Profhilo unique, why it is increasingly used for the neck, and the science behind its results.
What Is Profhilo?
Profhilo® is an injectable hyaluronic acid (HA) treatment developed by IBSA Derma. Unlike dermal fillers, Profhilo is not designed to volumize or sculpt but to remodel skin quality.
Key features:
High concentration HA: 64 mg/2 mL, one of the highest available.
Hybrid technology: A patented thermal process creates both high- and low-molecular weight HA chains.
Spreadability: Profhilo disperses evenly under the skin, stimulating hydration and collagen production across wider areas.
For official details, see the IBSA Derma Profhilo page (external official source).
Why Focus on Profhilo Neck?
The neck is highly susceptible to aging because:
The skin is thinner and produces less collagen.
Constant movement from swallowing, speaking, and "tech neck" postures deepen lines.
Sun exposure accelerates damage and elasticity loss.
Profhilo Neck works by improving hydration, elasticity, and firmness, making it one of the most effective non-surgical rejuvenation methods available.
How Does Profhilo Neck Work?

Biological Action
Hydration Boost
Low-molecular weight HA improves skin moisture balance.
Collagen and Elastin Stimulation
High-molecular weight HA provides structural support, stimulating fibroblasts.
Tissue Remodeling
Enhances dermal architecture, reducing laxity and fine crepiness.
Injection Technique
A Bio Aesthetic Point (BAP) technique is commonly used.
Multiple small injection sites across the neck allow Profhilo to spread evenly.
Evidence Supporting Profhilo Neck
Studies published in peer-reviewed journals demonstrate Profhilo’s ability to improve skin elasticity, hydration, and wrinkle depth in the face and neck region. Clinical reviews confirm safety and efficacy with minimal downtime compared to laser or surgical options.
Study Area | Key Findings |
Face & Neck skin quality | Improved hydration and elasticity over 8–12 weeks |
Neck lines & laxity | Reduction in fine lines and crepey texture |
Safety profile | Mild swelling and redness at injection points, resolving within 24–48 hours |
Treatment Journey with Profhilo Neck
1. Consultation
A doctor evaluates skin laxity and sets realistic expectations.
2. Procedure
Two sessions, one month apart, are standard.
Injections take about 15 minutes.
3. Results
Noticeable improvement after the second session.
Results last 6–9 months.
Who Is Suitable for Profhilo Neck?
Ideal candidates:
Mild to moderate skin laxity on the neck.
Patients in their 30s–60s noticing crepey or wrinkled texture.
Those who want natural, subtle improvement without volumization.
Not suitable for:
Pregnant or breastfeeding women.
Patients with severe sagging needing surgical lifting.
Individuals with HA allergies or active skin infections.
Comparing Profhilo Neck with Other Treatments
Treatment | Best for | Downtime | Longevity |
Profhilo Neck | Skin hydration, elasticity, fine lines | Minimal (24–48 hrs redness) | 6–9 months |
Dermal Fillers | Volume restoration, contouring | Mild bruising/swelling | 9–12 months |
Laser / RF | Collagen stimulation, tightening | 3–7 days recovery | 6–12 months |
Surgery (Neck Lift) | Severe sagging | 2–3 weeks | Long-term (5–10 years) |
Profhilo fills the gap between topical skincare and invasive surgery, making it an attractive option for many patients.
Safety & Side Effects of Profhilo Neck
Common: Temporary redness, swelling, or bruising at injection sites.
Rare: Small nodules or lumps, typically resolving within days.
Important: Must be administered by a licensed medical professional trained in advanced injectables.
Profhilo Neck Results: What to Expect
Timeline of improvement:
Week 1–2: Increased hydration, healthier glow.
Week 4–6: Noticeable tightening and smoothness.
Week 8–12: Maximum collagen remodeling and improved elasticity.
Benefits of Choosing Profhilo Neck
Natural-looking improvement (no overfilled appearance).
Stimulates your own collagen and elastin.
Suitable for both men and women.
Complements other treatments like Botox or energy-based devices.
Quick, low-downtime procedure.
For patients considering injectables in Singapore, you can also visit Neesoon Clinic – Profhilo Singapore for treatment information.
Summary: Profhilo Neck Rejuvenation
Profhilo Neck is a science-backed, minimally invasive treatment that enhances skin quality below the jawline. By hydrating deeply and stimulating collagen, it reduces crepiness, improves elasticity, and delivers a youthful, refreshed neck appearance.
With proven results, minimal downtime, and natural outcomes, Profhilo Neck is becoming a leading option for non-surgical neck rejuvenation worldwide.
Disclaimer:The information provided in this article is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The content is not intended to be a comprehensive source of information and should not be relied upon as such. Reliance on any information provided in this article is solely at your own risk. The authors and the publisher do not endorse or recommend any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned in the article. Any reliance on the information in this article is solely at the reader's own risk.
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